{"id":2579,"date":"2021-10-10T05:48:06","date_gmt":"2021-10-10T03:48:06","guid":{"rendered":"https:\/\/consumers-views.com\/lv\/?p=2579"},"modified":"2021-10-21T14:10:37","modified_gmt":"2021-10-21T12:10:37","slug":"minoksydyl-vai-finasterids","status":"publish","type":"post","link":"https:\/\/consumers-views.com\/lv\/minoksydyl-vai-finasterids\/","title":{"rendered":"Minoksydyl vai finaster\u012bds – alop\u0113cijas farmakolo\u0123isk\u0101 \u0101rst\u0113\u0161ana."},"content":{"rendered":"\n

Matu izkri\u0161ana tiek uzskat\u012bta par dabisku procesu<\/strong>, bet tikai tad, ja dien\u0101 izkr\u012bt ne vair\u0101k k\u0101 100-150<\/strong> mati\u0146u. Jebkur\u0161 liel\u0101ks daudzums liecina par probl\u0113mu<\/strong>, k\u013c\u016bdu ikdienas matu kop\u0161an\u0101 vai par organisma iek\u0161ien\u0113 att\u012bst\u012bju\u0161os slim\u012bbu, kuras viens no simptomiem ir matu izkri\u0161ana. Da\u017ek\u0101rt tas var b\u016bt tik intens\u012bvs, ka var pat izrais\u012bt piln\u012bgu baldriju<\/strong>, ja vien pirms tam netiek veikta atbilsto\u0161a \u0101rst\u0113\u0161ana. <\/p>\n\n\n\n

Ir daudz veidu, k\u0101 \u0161o procesu aptur\u0113t un daudzos gad\u012bjumos liel\u0101 m\u0113r\u0101 ar\u012b main\u012bt, un \u013coti popul\u0101ras ir dabisk\u0101s metodes,<\/strong> augu un gar\u0161augu izmanto\u0161ana, kas labv\u0113l\u012bgi ietekm\u0113 matu un galvas \u0101das vesel\u012bbu. Vien\u0101ds skaits cilv\u0113ku izv\u0113las alop\u0113cijas farmakolo\u0123isko \u0101rst\u0113\u0161anu<\/strong>, kur\u0101 galvenok\u0101rt tiek izmantotas divas vielas – minoksidils un finaster\u012bds<\/strong>.<\/p>\n\n\n\n

Matu izkri\u0161ana – k\u0101di ir iemesli?<\/h2>\n\n\n\n
\"<\/figure><\/figure><\/div>\n\n\n\n

\u0160o divu sp\u0113c\u012bgo farmaceitisko l\u012bdzek\u013cu lieto\u0161anai ir savas priek\u0161roc\u012bbas un tr\u016bkumi<\/strong>, kurus m\u0113s izkl\u0101st\u012bsim v\u0113l\u0101k \u0161aj\u0101 tekst\u0101, bet pirms tam ir v\u0113rts zin\u0101t, k\u0101p\u0113c k\u0101d\u0101 br\u012bd\u012b mati s\u0101k izkrist. Baldonijas c\u0113lo\u0146i<\/strong> ir da\u017e\u0101di,<\/strong> un to diagnostic\u0113\u0161ana var aiz\u0146emt ilgu laiku, un ar tiem j\u0101nodarbojas kvalific\u0113tai personai<\/strong>, dermatologam vai trichologam . <\/p>\n\n\n\n

Tikai vi\u0146iem ir atbilsto\u0161as un pla\u0161as zin\u0101\u0161anas<\/strong>, lai diagnostic\u0113tu iesp\u0113jam\u0101s slim\u012bbas, kas to izraisa, un gal\u0113jos gad\u012bjumos var b\u016bt nepiecie\u0161ama pat matu transplant\u0101cija. Daudzi matu izkri\u0161anas c\u0113lo\u0146i ir tie\u0161i atkar\u012bgi no mums<\/strong>, tie ir m\u016bsu pa\u0161u nolaid\u012bbas rezult\u0101ts. Ja v\u0113laties, lai j\u016bsu mati b\u016btu skaisti, biezi un dabiski sp\u012bd\u012bgi ilgu laiku, jums noteikti j\u0101piev\u0113r\u0161 uzman\u012bba<\/strong>.<\/p>\n\n\n\n

Pareizas di\u0113tas iev\u0113ro\u0161ana<\/h3>\n\n\n\n

Tikai nedaudzi cilv\u0113ki apzin\u0101s, ka nevesel\u012bgs uzturs ir ne tikai liek\u0101 svara un aptauko\u0161an\u0101s c\u0113lonis, bet tas var izrais\u012bt ar\u012b p\u0101rm\u0113r\u012bgu un pa\u0101trin\u0101tu plikpaur\u012bbu<\/strong>. Da\u017eos \u0101tr\u0101s \u0113din\u0101\u0161anas produktos vai augsti apstr\u0101d\u0101tos p\u0101rtikas produktos tr\u016bkst sast\u0101vda\u013cu<\/strong>, kas nepiecie\u0161amas matu un galvas \u0101das baro\u0161anai<\/strong>, kas neap\u0161aub\u0101mi ir.<\/p>\n\n\n\n

  • A vitam\u012bns,<\/strong> kas nosaka matu veidojo\u0161o \u0161\u016bnu pareizu veido\u0161anos, kuras k\u013c\u016bst sp\u0113c\u012bg\u0101kas un bl\u012bv\u0101kas, \u0161\u012b vitam\u012bna tr\u016bkums k\u013c\u016bst par iemeslu matu folikulu darb\u012bbas trauc\u0113jumiem, alop\u0113cija areata un redzes pasliktin\u0101\u0161an\u0101s;<\/li>
  • B2 vitam\u012bns<\/strong>, riboflav\u012bns, kas nov\u0113r\u0161 matu izkri\u0161anu, pie\u0161\u0137ir matiem vitalit\u0101ti un atjauno to sp\u012bdumu, samazina sebuma sekr\u0113ciju, kas var izrais\u012bt seborejas alop\u0113ciju.<\/li>
  • B3 vitam\u012bns<\/strong>, niac\u012bns, r\u016bp\u0113jas par pareizu matu v\u0101rpstas strukt\u016bru, nodro\u0161ina to ar intens\u012bvai aug\u0161anai nepiecie\u0161amo ener\u0123iju, uzlabo galvas \u0101das asins apg\u0101di;<\/li>
  • B5<\/strong> vitam\u012bns, pantot\u0113nsk\u0101be, kas atrodams daudzos matu kop\u0161anas l\u012bdzek\u013cos, stiprina un izl\u012bdzina matu strukt\u016bru, atjauno to pigment\u0101ciju un nov\u0113r\u0161 sirm\u0161anu. Tas labv\u0113l\u012bgi iedarbojas ar\u012b uz \u0101du, mitrinot to l\u012bdz dzi\u013c\u0101kajiem sl\u0101\u0146iem, aizkav\u0113jot noveco\u0161an\u0101s procesus, nov\u0113r\u0161ot iekaisumus un \u0101das slim\u012bbas, piem\u0113ram, pinnes ;<\/li>
  • B6 vitam\u012bnu<\/strong>, piridoks\u012bnu, kas pa\u0101trina jaunu matu aug\u0161anu;<\/li>
  • B7<\/strong> vitam\u012bns, biot\u012bns, kas veicina jaunu matu aug\u0161anu un nov\u0113r\u0161 matu izkri\u0161anu, mazina seboreju un blaugznas, nodro\u0161ina galvas \u0101das \u0161\u016bnu sk\u0101bekli un baro t\u0101s;<\/li>
  • C vitam\u012bns<\/strong>, askorb\u012bnsk\u0101be, ir \u013coti svar\u012bgs visam organismam, ne tikai m\u016bsu matu st\u0101voklim, sp\u0113c\u012bgs antioksidants, kas pat “aizv\u0101c” br\u012bvos radik\u0101\u013cus, reakt\u012bv\u0101s sk\u0101bek\u013ca formas (ROS), kas boj\u0101 \u0161\u016bnas. Tas piedal\u0101s kolag\u0113na – audu, tostarp matu, b\u016bvmateri\u0101la – sint\u0113z\u0113 un r\u016bp\u0113jas par to, lai uztur\u0113tu pareizo dzelzs l\u012bmeni, kas ir elements, kur\u0161 nepiecie\u0161ams, lai aptur\u0113tu matu izkri\u0161anu;<\/li>
  • sil\u012bcijs<\/strong>– elements, kas kop\u0101 ar cit\u0101m uzturviel\u0101m no p\u0101rtikas stiprina nov\u0101jin\u0101tus matu folikulus un saknes, vienlaikus nov\u0113r\u0161ot p\u0101rm\u0113r\u012bgu matu l\u016b\u0161anu.<\/li>
  • cinka<\/strong>, kas ir otrais elements matu un galvas \u0101das vesel\u012bb\u0101, kas galvenok\u0101rt ir nepiecie\u0161ams kerat\u012bna – specifiska prote\u012bna, kas kop\u0101 ar kolag\u0113nu ir v\u0113l viens matu celtniec\u012bbas materi\u0101ls, – veido\u0161anai.<\/li>
  • sel\u0113ns<\/strong>, kas nodro\u0161ina ne tikai sp\u0113c\u012bgu matu strukt\u016bru, bet ar\u012b to elast\u012bbu un, pateicoties pretiekaisuma un prets\u0113n\u012b\u0161u \u012bpa\u0161\u012bb\u0101m, nov\u0113r\u0161 galvas \u0101das infekcijas un iekaisumus.<\/li><\/ul>\n\n\n\n

    K\u013c\u016bdas ikdienas matu kop\u0161an\u0101<\/h3>\n\n\n\n

    V\u0113l viens matu izkri\u0161anas c\u0113lonis, kura d\u0113\u013c ir nepiecie\u0161ams veikt farmakolo\u0123isku alop\u0113cijas \u0101rst\u0113\u0161anu<\/strong> ar minoksidilu vai finaster\u012bdu, ir k\u013c\u016bdas, kas pie\u013cautas ikdienas matu kop\u0161anas rut\u012bnas<\/strong> laik\u0101. To ar\u012b nevajadz\u0113tu nov\u0113rt\u0113t par zemu, un speci\u0101listi, tostarp iepriek\u0161 min\u0113tie trichologi, iesaka.<\/p>\n\n\n\n

    • r\u016bp\u012bga \u0161amp\u016bnu un kondicionieru izv\u0113le matiem, to sast\u0101vs, kam j\u0101b\u016bt piln\u012bgi dab\u012bgiem, bez t\u0101d\u0101m viel\u0101m k\u0101 silikons, SLS-y vai \u012bpa\u0161i kait\u012bgiem parab\u0113niem;<\/li>
    • nesasiet garus matus ar gumiju, ja tie ir pak\u013cauti vair\u0101ku stundu spiedienam, kas izraisa to v\u0101jin\u0101\u0161anos un aizvien bie\u017e\u0101ku izkri\u0161anu;<\/li>
    • nelietot matu taisnot\u0101jus, kas tos uzkars\u0113 l\u012bdz \u013coti augstai temperat\u016brai, kas ietekm\u0113 to st\u0101vokli, boj\u0101 to strukt\u016bru, liek tiem l\u016bzt, drupin\u0101ties un “izn\u0101kt” sauj\u0101s. L\u012bdz\u012bgu negat\u012bvu ietekmi rada ar\u012b f\u0113na lieto\u0161ana, t\u0101p\u0113c lab\u0101k ir \u013caut matiem p\u0113c mazg\u0101\u0161anas iz\u017e\u016bt dabiski.<\/li><\/ul>\n\n\n\n

      Slim\u012bbas, kas izraisa baldness<\/h3>\n\n\n\n

      Cita starp\u0101 t\u0101s ir blakusslim\u012bbas, kas<\/strong> bie\u017ei paliek neatkl\u0101tas un izpau\u017eas k\u0101 strauja matu retin\u0101\u0161an\u0101s<\/strong>, autoim\u016bn\u0101s slim\u012bbas, im\u016bnsist\u0113mas pav\u0101jin\u0101\u0161an\u0101s, vairogdziedzera slim\u012bbas, t\u0101 p\u0101rm\u0113r\u012bga vai nepietiekama darb\u012bba vai Hashimoto, ne\u0101rst\u0113jams iekaisums. Tikpat negat\u012bva ietekme ir ar\u012b sp\u0113c\u012bgam stresam, depresijai un citiem nervu spriedzes st\u0101vok\u013ciem. Protams, ka plikpaur\u012bbu var izrais\u012bt ar\u012b tipiskas \u0101das slim\u012bbas<\/strong>, un visbie\u017e\u0101k nor\u0101d\u012bt\u0101s ir:<\/p>\n\n\n\n

      • seborejas dermat\u012bts;<\/li>
      • hroniska mycosis fungoides, ar\u012b galvas \u0101das;<\/li>
      • atopiskais dermat\u012bts (AD);<\/li>
      • hronisks g\u016b\u017eas folikul\u012bts;<\/li>
      • psori\u0101ze;<\/li>
      • \u0101das audz\u0113ji.<\/li><\/ul>\n\n\n\n

        Farmakolo\u0123isk\u0101 alop\u0113cijas \u0101rst\u0113\u0161ana – k\u0101p\u0113c to izmanto<\/h2>\n\n\n\n

        K\u0101 redzat, ir daudz<\/strong> plikpaur\u012bbas c\u0113lo\u0146u<\/strong>, t\u0101p\u0113c nav p\u0101rsteidzo\u0161i, ka vairums slimu cilv\u0113ku v\u0113las izmantot farmakolo\u0123isko \u0101rst\u0113\u0161anu, kas ir efekt\u012bva,<\/strong> bet ne piln\u012bgi<\/strong> dro\u0161a<\/strong>. Tas ir dabiski, galu gal\u0101, kad m\u0113s saslimstam, pirmais, kas mums n\u0101k pr\u0101t\u0101, ir viz\u012bte pie speci\u0101lista, lai \u0101rst\u0113tu konkr\u0113to slim\u012bbu. Tikai vi\u0146i var izrakst\u012bt tikai recep\u0161u<\/strong> medikamentus, tostarp tos, kuru galven\u0101s akt\u012bv\u0101s sast\u0101vda\u013cas ir minoksidils <\/strong>vai finaster\u012bds<\/strong>. <\/p>\n\n\n\n

        T\u0101p\u0113c ir v\u0113rts t\u0101s raksturot s\u012bk<\/strong>\u0101k, uzzin\u0101t par to lieto\u0161anas priek\u0161roc\u012bb\u0101m un blakuspar\u0101d\u012bb\u0101m, ko t\u0101s izraisa. Abi savienojumi tiek izmantoti da\u017e\u0101du veidu plikpaur\u012bbas \u0101rst\u0113\u0161an\u0101, bet visefekt\u012bv\u0101k tie mazina androg\u0113n\u0101s<\/strong> alop\u0113cijas simptomus. Tam var b\u016bt da\u017e\u0101di c\u0113lo\u0146i, bet liel\u0101koties tiek min\u0113ta \u0123en\u0113tiska, no vec\u0101kiem \u0123imenes locek\u013ciem p\u0101rmantota tendence<\/strong>.<\/p>\n\n\n\n

        Androg\u0113nisk\u0101 alop\u0113cija, kas t\u0101 ir un kas to izraisa<\/h2>\n\n\n\n

        Run\u0101jot par androg\u0113nu alop\u0113ciju<\/strong>, m\u0113s dom\u0101jam par vienu no visgr\u016bt\u0101k \u0101rst\u0113jamiem \u0161\u012bs slim\u012bbas variantiem, kas saist\u012bts ar matu aug\u0161anas f\u0101z\u0113m<\/strong>. Tie k\u013c\u016bst jut\u012bgi pret t\u0101 sauktajiem androg\u0113niem, \u012bpa\u0161i pret vienu no to variantiem – dihidrotestosteronu<\/strong>, kas lab\u0101k paz\u012bstams ar sa\u012bsin\u0101to nosaukumu DHT. <\/p>\n\n\n\n

        Tas veidojas, p\u0101rveidojot dzimumhormonu testosteronu, ko s\u0101k ietekm\u0113t enz\u012bms 5 alfa-redukt\u0101ze. \u0160\u012b jaun\u0101 forma s\u0101k negat\u012bvi<\/strong> ietekm\u0113t matu folikulus, s\u0101kotn\u0113ji tos v\u0101jinot, p\u0113c tam izraisot to pak\u0101penisku sarau\u0161anos<\/strong> un visbeidzot n\u0101vi<\/strong>. Ja netiek veikta atbilsto\u0161a \u0101rst\u0113\u0161ana, matu izkri\u0161ana var b\u016bt piln\u012bga un neatgriezeniska.<\/p>\n\n\n\n

        Minoksidils vai finaster\u012bds, ko lietot<\/h2>\n\n\n\n

        Viens no veidiem, k\u0101 \u0101rst\u0113t androg\u0113no alop\u0113ciju, ir izmantot sp\u0113c\u012bgus farmaceitiskos l\u012bdzek\u013cus,<\/strong> kas ir iek\u013cauti vair\u0101kos medikamentos, tostarp berz\u0113jumos un toniz\u0113jo\u0161os l\u012bdzek\u013cos, kas paredz\u0113ti \u0161\u012bs slim\u012bbas att\u012bst\u012bbas aptur\u0113\u0161anai. \u012apa\u0161i tiek izmantoti divi, kas at\u0161\u0137iras p\u0113c sav\u0101m \u012bpa\u0161\u012bb\u0101m, iedarb\u012bbas un<\/strong> diem\u017e\u0113l ar\u012b<\/strong> izrais\u012btaj\u0101m blakuspar\u0101d\u012bb\u0101m<\/strong>.<\/p>\n\n\n\n

        Minoksydyl – \u012bpa\u0161\u012bbas<\/h3>\n\n\n\n

        T\u0101s nepul\u0113ts, zin\u0101tniskais nosaukums ir minoxidil <\/strong>, un to j\u016bs atrad\u012bsiet, lasot baldness z\u0101\u013cu sast\u0101vu, ko v\u0113laties lietot. Tas ir organisks \u0137\u012bmisks savienojums, ko izgudroja amerik\u0101\u0146u farm\u0101cijas uz\u0146\u0113mums Upjohn Company pag\u0101ju\u0161\u0101 gadsimta 50. gados un kas ir dihidralaz\u012bna atvasin\u0101jums. S\u0101kotn\u0113ji izgudrot\u0101js un ra\u017eot\u0101js to bija iecer\u0113jis k\u0101 l\u012bdzekli ku\u0146\u0123a \u010d\u016blu \u0101rst\u0113\u0161anai<\/strong>, ta\u010du izr\u0101d\u012bj\u0101s, ka tas visefekt\u012bv\u0101k iedarbojas uz hipertensiju<\/strong>. Tikai p\u0113c k\u0101da laika tika paman\u012bts, ka viens no t\u0101s “blakusefektiem” ir pa\u0101trin\u0101ta matu aug\u0161ana<\/strong>, t\u0101p\u0113c dr\u012bz vien to iek\u013c\u0101va prepar\u0101tos, kas paredz\u0113ti pa\u0101trin\u0101tas baldriozes nov\u0113r\u0161anai.<\/p>\n\n\n\n

        Minoksydyl – darb\u012bba<\/h3>\n\n\n\n
        \"<\/figure><\/figure><\/div>\n\n\n\n

        Minoksidila iedarb\u012bba pret matu izkri\u0161anu ir balst\u012bta uz m\u0113r\u0137tiec\u012bgu matu aug\u0161anas f\u0101zes, t. i., anag\u0113na, indukciju<\/strong>. Vienlaikus tas uzlabo galvas \u0101das apasi\u0146o\u0161anu, pateicoties t\u0101 \u012bpa\u0161\u012bb\u0101m papla\u0161in\u0101t<\/strong> mazos asinsvadus. Tas ir efekt\u012bvs pat gandr\u012bz 48%<\/strong> l\u012bmen\u012b, un tik daudziem v\u012brie\u0161iem tika nov\u0113rota jaunu matu aug\u0161ana. <\/p>\n\n\n\n

        Tas palielina asins pl\u016bsmu uz matu folikuliem un matu s\u012bpoliem, t\u0101d\u0113j\u0101di stimul\u0113jot to intens\u012bv\u0101ku darb\u012bbu<\/strong> un nodro\u0161inot tos ar nepiecie\u0161amaj\u0101m bar\u012bbas viel\u0101m. \u0160\u012bs minoksidila \u012bpa\u0161\u012bbas \u013cauj to izmantot iedzimtas alop\u0113cijas,<\/strong> t. i., androg\u0113n\u0101 varianta, \u0101rst\u0113\u0161an\u0101.<\/p>\n\n\n\n

        Minoksydyl – blakuspar\u0101d\u012bbas<\/h3>\n\n\n\n

        Uz minoksidilu balst\u012btu prepar\u0101tu augst\u0101 efektivit\u0101te mudina to lietot, ta\u010du pirms tam ir j\u0101zina visas \u0161\u0101da l\u0113muma sekas vesel\u012bbai<\/strong>. Tas ir \u0137\u012bmisks savienojums, ko nevar lietot visi, un visbie\u017e\u0101k sastopam\u0101s kontrindik\u0101cijas<\/strong> ir:<\/p>\n\n\n\n